I have a setup for email that would be a good preparation for email on the Pre.
I recommend that you buy a personal domain name. When your email accounts move around, you can keep the same email address and simply redirect it to wherever you go.
I have been testing different email setups for my Treo. I was interested in Gmail and Mobile Me. It turns out that Blazer works well with Gmail but Mobile Me does not. I wound up sending 3 copies of email from my personal domain name email. One goes to my local cable company email, one to Gmail, and one to Mobile Me. I was testing to see what worked best.
This sort of setup is also great for preparing for the Pre. Now I can use Gmail on the Pre and see my received emails several months back.
If I had been using Gmail IMAP, I'd also have sent emails available on the Pre.
PS: You don't need a regular email on your personal domain - all you need to do is use email forwarding to Gmail or other email accounts.