So let's say I use Google Calendar on my laptop to schedule appointments, or even use iCal and sync that with BusySync>Gcal>Pre
If I schedule an appointment in Gcal how can I get a notification/reminder to pop up on my Pre?
I have the same setup. iCal>Google>Pre with BusySync taking care of the iCal>GCal piece. Be sure that you have your BusySync preferences set to send Alarms to Google as pop-ups and you will get the pop-up alert on the pre at the appropriate time. Also, when you create an event on the pre with an alarm notification, it will set your default iCal notification as well.