I really thought my above post would have created a little bit of interest. In any case, I have had 2.1 on my Pre Plus and then got the Vzw Pre 2 and used 2.0.1 for a few days then put 2.1 on it yesterday.
I have looked at some of the reported bugs and it seems that 2.1 fixed some on my Pre 2:
Media Sync: I can copy an album to my usb, disconnect, open Music ReMix and see the newly loaded artist and play the music
Pictures: I can take a picture, view it, delete it, take another picture, and when I view it, it shows me the most recent picture.
Calender reminder: If I click on the Remind in 5 minutes, my calender reminder will pop up in five minutes.
Email: I can view my pop emails properly. With 2.0.1, the same emails were showing a black box. I can also click on an attachment, like a Word document, and it opens properly in Quickoffice.
SMS: I don't seem to get the delay on this phone, either with 2.0.1 or 2.1. I did get it on my Pre + with 2.1.
Dr: The 2.0.1 doctor will wipe your USB. The 2.1 doctor will not.
I don't know about some of the other bugs, but I have not had any restarts or locked apps. My Help app works and shows the Tips, Clips, etc. I'm willing to try out some of the other bugs, but I would urge people to consider putting the 2.1 on their phone using Andidendel's script. The only disadvantage I would see is that if Verzion came out with an update, you might have to Doctor, but 2.1 does such a good job of backing things up, it's pretty easy.
Forgot to say that you won't be able to get Skype with this, but I didn't use that anyhow in the Phone app.