I had a bunch of patches on it when I first got it, but I doctored it because I thought there was a conflict somewhere. It was just an issue with Facebook syncing contact photos. Turns out it wasn't a patch issue. I had these installed:
Add scrollbars to the browser
Increase Touch sensitivity and smoothness
Muffle System Logging
Mojo FPS booster
Battery Percent and Horizontal Icon
I'd say to also get JStop, and turn on auto gc. Also be sure to turn on notifications. My phone ran real smooth after that. Derek recommended the majority of those, and it definitely helped. Also downloaded Flashlight in Device Menu, Internalz, and Theme Manager, but those don't speed anything up. Just personal preferences.